Komi-san Has a Communication Disorder.
Timid Tadano is a total wallflower, and that’s just the way he likes it. All that changes when he finds himself alone in a classroom on the first day of high school with the legendary Komi-san. He quickly realizes she isn’t aloof—she has trouble communicating. Now he’s made it his mission to help her on her quest to make 100 friends!
Komi-san is an adaptation of an ongoing manga with two anime seasons.
The locations featured in Komi-san are mostly focused around Yokohama and wider Kanagawa, but there are some excursions out to different “class trip” type locations, most importantly Osaka and Manhattan.
Sources
Kinda Neet – Is Komi Can’t Communicate set in a REAL PLACE? – [Youtube]